This vaccine is different from current flu vaccines because it targets the proteins inside the flu virus rather than the proteins on the external coat. These interior proteins are similar across all strains of the flu and less likely to mutate, so this one vaccine could be used to prevent all types of flu. Another difference is that this new treatment helps boost the production of T-cells which can identify, attack, and kill infected cells. So it's much more effective than today's vaccine that just stimulates the body to produce antibodies to fight the flu. If this new vaccine is successful, it could prevent future nasty outbreaks like the swine flu and H1N1.
I don't know about you, but it'd be a huge relief during cold and flu season to get one shot and know I'd never have to suffer in bed surrounded by snotty tissues again.