On Letterman last night, Jason Segel discussed what drove him to lose some major weight after hitting 245 pounds. Watch the video to hear Jason's story and what caused Dave to exclaim, "Honest to God, Jason, this looks like a crime scene!" Thirty pounds later, Jason is looking pretty good and seems totally OK that he lost a starring film role to James Van Der Beek (aka Dawson's Creek) way back when.
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