Diphenhydramine (On the skin)

Introduction

Diphenhydramine (dye-fen-HYE-dra-meen)

Treats pain and itching caused by insect bites, minor cuts or burns, or sunburn. Also treats skin rash caused by poison ivy, poison oak, or poison sumac.

Brand Name(s)

Dermamycin, Benadryl Extra Strength, Derma-Pax

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to diphenhydramine. Do not use this medicine for chickenpox or measles. Do not use on large areas of skin, or on rash areas that have blisters or broken skin. You should not use this medicine if you are also taking diphenhydramine (Benadryl®) by mouth.

How to Use This Medicine

Gel/Jelly, Cream, Ointment, Spray, Lotion

• Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
• If you are using this medicine without a prescription, follow the instructions on the medicine label.
• Do not apply the medicine more than 4 times each day.
• This medicine is for use on the skin only. Do not get it in your eyes, nose, or mouth. Do not use it on skin areas that have cuts or scrapes. If it does get on these areas, rinse it off right away.
• Wash your hands with soap and water before and after using this medicine.
• Apply a thin layer to the affected area. Rub it in gently.
• Do not cover the treated area with a bandage unless your doctor has told you to.

If a dose is missed:

• If you miss a dose or forget to use your medicine, apply it as soon as you can. If it is almost time for your next dose, wait until then to apply the medicine and skip the missed dose. Do not apply extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
• Ask your pharmacist, doctor, or health caregiver about the best way to dispose of the used medicine container and any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
• Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Do not use cosmetics or other skin care products on the treated skin areas.

Warnings While Using This Medicine

• Make sure your doctor knows if you are pregnant or breast feeding.
• If your symptoms do not improve or if they get worse, call your doctor.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

• Worsened skin rash, itching, redness, or swelling.

If you notice these less serious side effects, talk with your doctor:

• Return of your skin symptoms a few days after they have cleared up.