Coagulation Factor VIIa (koh-a-gyoo-LAY-shun FAK-tor SEV-en A)
Treats and prevents bleeding episodes in people who have hemophilia A or B with inhibitors to Factor VIII or Factor IX.
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not use this medicine if you have had an allergic reaction to coagulation factor (recombinant), or to mouse, hamster, or bovine proteins (found in drugs such as abciximab, darbepoetin alfa, infliximab, Aranesp®, Remicade®, Rituxan®, or Reopro®).
How to Use This Medicine
- Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
- A nurse or other trained health professional will give you this medicine.
- You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
- Use a new needle and syringe each time you inject your medicine.
- This medicine is a powder that must be mixed with a special liquid (sterile water) before you use it. The sterile water should come in the same package with the medicine. Let both the powdered medicine and the sterile water warm to room temperature before you mix them together.
- This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.
If a dose is missed:
- Call your doctor, pharmacist, treatment clinic, or home health caregiver for instructions.
How to Store and Dispose of This Medicine
- If you store this medicine at home, keep it in the refrigerator. Do not freeze.
- If you cannot use the medicine right after you mix it, you can store it at room temperature or in the refrigerator. You must use the medicine within 3 hours of mixing.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. You will also need to throw away old medicine after the expiration date has passed.
- Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breast feeding, or if you have a history of kidney disease, or blood clots known as disseminated intravascular coagulation (DIC). Tell your doctor if you have any arterial diseases (such as blocked or hardened arteries), an infection, or any untreated wounds.
- Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
- If your symptoms do not improve or if they get worse, call your doctor.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
- Cough, chest pain, or shortness of breath.
- Decrease in how much or how often you urinate.
- Fever or chills.
- Red or dark-brown urine, or black stool.
- Redness, pain, or swelling where the IV is given.
- Unusual bleeding, bruising, or weakness.