Lotus is the traditional seat for mediation. You can just sit comfortably in your desk chair, with your neck and spine straight and erect, to begin to calm your brain. Place your hands palms up, with the thumbs and first fingers touching. If practical in the office setting, practice crossing your legs to build up the Lotus position. This will help free your spine from the stress of sitting at your desk all day. Traditional Sanskrit texts say that Padmasana, aka Lotus, destroys all disease. Note: Lotus is a two-sided pose, so be sure to practice both leg crosses.
Photo courtesy of Fila