If you're looking to build lean muscle mass, taking oral contraceptives might be interfering with all your hard work. A recent study from Texas A&M University, involving 73 generally healthy women between 18 and 31, found that women not taking birth control pills gained 60 percent more muscle mass than women on the pill during a 10-week time period.

All the women in the study participated in the same whole-body resistance exercise training program and worked out three times a week under the supervision of exercise physiologists, but half were using oral contraceptives and the other half were not. All the women performed the same exercises, same number of reps, at the same intensity. The study participants were also encouraged to increase their intake of protein, by about a third more than nutritional guidelines, to ensure they wear eating enough protein to build muscle mass. After the 10-week workout period, the women who were not on the pill had significantly more lean muscle mass.

Information on both groups hormone levels, when you read more.

A comparison of blood samples between the two groups indicated the women using oral contraception had less testosterone in their system, a hormone necessary for making muscle. In addition, women on the pill had more cortisol in their systems, which is a hormone that helps break down muscle tissue.

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